https://nanoclayguide.com/tags/controlled-release/Recent content in Controlled Release on Nanoclay GuideHugoen-usMon, 23 Mar 2026 00:00:00 +0000https://nanoclayguide.com/blog/halloysite-nanotubes-drug-delivery/Mon, 23 Mar 2026 00:00:00 +0000https://nanoclayguide.com/blog/halloysite-nanotubes-drug-delivery/<p>Most engineered drug delivery nanoparticles — liposomes, PLGA nanoparticles, mesoporous silica — require sophisticated synthesis, careful quality control, and high manufacturing costs. Halloysite nanotubes come out of the ground already shaped like containers. The hollow tubular structure, formed over geological timescales by the natural rolling of aluminosilicate layers, provides a built-in reservoir for loading active pharmaceutical ingredients. No complex fabrication needed.</p> <p>This structural accident of geology has made halloysite the most actively studied nanoclay for biomedical applications. The research volume has grown exponentially since 2010, with hundreds of publications annually exploring drug loading, controlled release kinetics, toxicity profiles, and potential clinical applications. Here&rsquo;s where the science stands — and where the gaps remain.</p>